The National Down Syndrome Society is the leading human rights organization for all individuals with Down syndrome.The National Down Syndrome Society envisions a world in which all people with Down syndrome have the opportunity to enhance their quality of life, realize their life aspirations and become valued members of welcoming communities. Through our toll-free helpline (800-221-4602) and email service ([email protected]), NDSS receives more than 10,000 requests a year for information on Down syndrome.